Ortobrand | ORTHOFLEX one®

ORTHOFLEX® one//Natural cross linked hyaluronate. The only single injection.

Prefilled syringes|

A new generation of viscosupplement

Natural Cross-linked Hyaluronate 60 mg + Chondroitin Sulfate 90mg / 3ml

Description

ORTHOFLEX one® is single treatment , viscoelastic gel injectable prefilled syringe used intra articular for treating arthritis. It is similar to synovial fluid, a substance that occurs naturally in the joints, synovial fluid acts as a lubricant and shock absorber.
ORTHOFLEX one® is cross~linked hyaluronate 60mg/3ml solution of highly purified sodium hyaluronate + chondroitin sulfate 90mg/3ml, with high molecular weight that guarantees its excellent efficiency and a strong therapeutic effect (3,0 million daltons).
Obtained by bio fermentative process, synthetic origin gives a complete safety eliminating any allergic reactions.
ORTHOFLEX one® is a prefilled syringes having aluminum blister for sealing that assure 3 years guarantee of validity , sterilized by autoclave,

Effects

Chondroitin Sulfate and Hyaluronic Acid with ORTHOFLEX one® in the treatment of degenerative joint disease.

Hyaluronan contributes to the synovial fluid’s lubricating properties and also controls fluid flow into and out of the joint space.
Injected into knee joints with osteoarthritis (OA) to ease pain and stiffness. Chondroitin sulfate, is a structural component of aggrecan in cartilage and provides much of its resistance to compression.
Chondroitin sulfate (CS) and hyaluronic acid (HA) induces cartilage destruction and acts as a mediator of the inflammatory response.
Using Chondroitine Sulfate as a cross-linking agent increase biocompatibility and biodegradability native polymer and creates premises delay of cartilage degeneration and even supports regeneration cartilage structure.
ORTHOFLEX one® –improved by cross linking , preponderantly elastic, confers capacity mechanic protection increased and improved lubrication( ≥45Pa characteristic human synovial fluid)

Indications

The treatment consists in administration of intra-articular single treatment :

ORTHOFLEX one® is indicated for the symptomatic treatment of mild of severe osteoarthritis.
Orthoflex one is recommended for patients that have joints pain coupled with reduced mobility. These symptoms can occur as a result of degenerative disease or trauma.
ORTHOFLEX one® treats pain and restricted mobility and elasticity , protect cartilage as a result of traumatic pathology in the knee joint and other synovial joints( hip, ankle, shoulder, elbow, wrist, fingers, toes, and the temporomandibular and facet joints)
Is also indicated for the reduction of post–arthroscopy pain.
Is contraindicated in children, pregnant or breast–feeding women.

Physicochemical Properties:

The treatment consists in administration of intra-articular single treatment :